Armata Pharmaceuticals is a World Leader in Bacteriophage Science
At Armata Pharmaceuticals, we have built a challenging and dynamic work environment that values talent, initiative, collaboration and commitment.
We are seeking passionate and dedicated individuals eager to join our scientific team to develop the next-generation of antimicrobial therapies based on harnessing the power of bacteriophage through synthetic biology.
Armata Pharmaceuticals is an equal opportunity employer. We recognize the importance of a diverse employee population and encourage applicants with various backgrounds and experiences. All qualified applicants will be considered for employment and will not be discriminated against on the basis of race; color; religion; genetic information; national origin; gender; sexual orientation; pregnancy, childbirth, or related medical conditions; familial status; age; disability; military or veteran status; or any other protected class under federal, state, or local law.
Open Positions
Facilities Supervisor
About this Position:
We are seeking a highly motivated individual to join our team as the Facilities Supervisor. The Facilities Supervisor will act as the key liaison to the department to lead all supply chain activities, manage inventory and equipment orders for our Glencoe and McConnell worksite, ensure that all records are maintained as necessary to satisfy standard operating procedures (SOPs) and good manufacturing practice (GMP) requirements. Additional responsibilities are to lead the project management of all inventory programs at the Armata clinical sites and implement inventory management strategies as well as update the facilities department software programs. The Facilities Supervisor will Coordinate with the purchasing department to ensure that all documentation is completed for proper accounting reconciliation and purchase order reconciliation of all expenses and received materials. Lastly, they will provide necessary training, ongoing coaching, and performance management to direct reports. This is a full-time position reporting to the Facilities Manager.
Job description and technical requirements:
- Familiar with using enterprise resource planning (ESP) software. Plus, licensed power user for Intacct Accounting software
- Responsible for performance and task management for direct reports.
- Support facility maintenance, equipment maintenance and inventory consumables.
- Ensure the schedules and work orders are executed at the proper time.
- Knowledge of domestic and international shipping requirements. Plus, experience with international shipping requirements and working with customs and regulations in a timely manner.
- Maintain backlog files of work orders awaiting scheduling in accordance with priority and requested completion date.
- Complete requisition forms, vendor follow ups, receive, process, and initiate all lab material requests in a timely fashion.
- Interface with multiple lab material suppliers to achieve cost cutting strategies.
- Reconcile inventory list for GMP and non GMP operations.
- Ensure that purchase orders are created and approved in a timely fashion.
- Interface with the Quality Control department to coordinate the release of quarantined GMP materials.
- Interface with the GMP operations team to quarantine and release required production materials.
- Monitor systems to identify performance risks and implement risks reduction strategies.
- Ensure safety needs are given top priority in work planning and scheduling.
- Ensure that Standard Operating Procedures (SOPs), current good manufacturing practices (GMPs) and all other regulatory requirements are followed.
- Revise SOPs and other controlled documentation as necessary.
- Assist the Facilities Manager by providing refresher training to various departments.
- Be proficient in MS office and demonstrate strong computer software skills.
- Lead project management to determine co-effective measures needed to improve the accuracy of estimating and/or improving methods of doing work.
- Excellent written and verbal communication skills.
- Collaborative mindset when working with various departments (Clinical, Product Development, Analytical and non GMP operation)
- Accountable to the manager and the team for facilities performance
- Additional duties as assigned.
Qualifications and Experience:
- Bachelor’s degree is preferred. Basic qualification, Highschool Degree and nine (9) years of facility maintenance experience.
- At least five (5) years of experience supervising staff.
- A minimum of five (5) years of maintenance experience in a biotech or pharmaceutical company with direct experience of GMP requirements for facility operations.
- Demonstrate proficiency with the current code of Federal Regulations (CFRs) and Current Good Manufacturing practices (cGMP)
- Excellent verbal and written communication skills.
- Sufficient understanding of process, systems, and equipment to troubleshoot problems and provide solutions to management.
- Able to prioritize multiple tasks and work under time constraints.
- Must have a strong work ethic and demonstrate dependability and timeliness.
- Self-starter with superior analysis and problem-solving skills and illustrates the ability to work with minimal supervision. Strong team-player and able to work well in small groups.
Physical Working Conditions:
This is a full– time position for work in a laboratory environment. The position requires wearing personal protective equipment. Occasionally, may require lifting or moving equipment up to 20 pounds and may require standing for extended durations throughout the day. Upon request, reasonable accommodations will be offered to enable individuals with disabilities to perform essential functions. There is little to no travel required of this position, with the exception of required training and possible conference or event attendance.
About Armata Pharmaceuticals, Inc.
Armata is a clinical-stage biotechnology company focused on the development of precisely targeted bacteriophage therapeutics for the treatment of antibiotic-resistant infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of the United States and Canada, Armata is developing proprietary synthetic phage candidates to target an undisclosed infectious disease agent. Armata is committed to advancing phage with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.
Pay: $95,000 - $120,000 - per year
Send cover letter and CV to: careers@armatapharma.com
Manufacturing Associate
About this Position:
We are seeking a highly motivated individual to join our company as a Manufacturing Associate. This position reports to the Manufacturing Manager and will work within a Manufacturing team to produce pharmaceutical products in a laboratory environment following Good Manufacturing Practices (GMP). This is a great opportunity to begin a Manufacturing career in the biotech industry. Our ideal candidate is someone with a willingness to learn, result-oriented, and a good team player.
Job description and technical requirements:
- Initiate, setup, and operate production equipment to manufacture pharmaceutical products. Production equipment utilized includes, but is not limited to: Fermenters, Pumps and filters, Tangential flow filtration systems, FPLC systems, Small volume liquid fillers
- Plan, initiate, setup, and manufacture bulk quantities of pharmaceutical products in a controlled environment according to production batch records within current Good Manufacturing Practices (cGMP)
- Review and maintain logbooks, production records, and associated documents to comply with regulatory requirements, cGMPs, and Standard Operating Procedures (SOPs).
- Clean and sample processing equipment and manufacturing areas according to SOPs.
- Other duties as assigned.
Qualifications and Experience:
- Bachelor’s degree, preferably in a science or engineering field.
- In lieu of a bachelor’s degree, will consider a minimum of three (3) years closely related experience in a GMP or clean room assembly environment with an Associate Degree or six (6) years closely related experience in a GMP or clean room assembly environment with a High School Diploma or equivalent.
- Demonstrated ability to be organized and work independently and in small work groups.
- Must be able to assist in trouble shooting activities and repairs to production equipment.
- Demonstrated mathematical skills, including the ability to perform addition, subtraction, multiplication, division, and conversions.
- Detail oriented. Demonstrated ability to read, comprehend, and follow written instructions.
- Demonstrated written and verbal communication skills are required.
- Experience in a related GMP environment within biotechnology/pharmaceutical industry strongly preferred.
- Must be able to learn and perform basic computer operations such as MS Office and Outlook and other computer-based software.
Physical Demands and Requirements:
This is a full– time position for work in a laboratory environment. The position requires wearing personal protective equipment. Occasionally, may require lifting or moving equipment up to 20 pounds and may require standing for extended durations throughout the day. Upon request, reasonable accommodations will be offered to enable individuals with disabilities to perform essential functions. There is little to no travel required of this position, with the exception of required training and possible conference or event attendance.
About Armata Pharmaceuticals, Inc.
Armata is a clinical-stage biotechnology company focused on the development of precisely targeted bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of the United States and Canada, Armata is developing proprietary synthetic phage candidates to target an undisclosed infectious disease agent. Armata is committed to advancing phage with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.
Pay: $28.00 - $35.00 per hour
Send cover letter and CV to: careers@armatapharma.com
Validation Manager
About this position:
The Validation Manager will be involved in validation projects at Armata’s existing and new cGMP facilities in Marina del Rey, CA, for biological products manufacturing. This is a superb opportunity for candidates considering a validation management career in biotechnology or the life sciences.
Key Accountabilities:
Ethical conduct and compliance
Ensures compliance of self and others to internal and external procedures/regulations.
Fiscal and financial control
Follows financial policies, manages people resources to policy requirements and delivers budgets.
People management
Optimizes performance outcomes of direct reports and ensures individuals understand the contribution they make.
Leadership and engagement
Understands the big picture and connects individuals to it in a meaningful way.
Compliance
Is accountable for ensuring compliance is understood and maintained across own functional area. Ensures that the required initial and continuing training of the department personnel and organization is carried out and adapted per need.
Job description and technical requirements:
- Develops and directs intermediate and finished product qualification and validation program encompassing facilities, utilities, aseptic processing, equipment, automated controls/ computer systems, process/product, cleaning, and shipping.
- Write and review qualification and validation documents (Master Plan, SOPs, URS, DQ, IQ, OQ, PQ, and PPQ/PV, etc. in compliance with corporate standards, good scientific and statistical concepts, and regulatory requirements.
- Coordinate qualification and validation trials and testing.
- Coordinate, prepare, review and/or approve comprehensive reports compliant with cGMP regulations and Good Documentation Practices. Review validation packages for completeness and accuracy, sound rationale, compliance with validation policies and procedures, and accurate data analysis.
- Compare results against acceptance criteria and work to resolve exceptions and deviations.
- Performs and oversees criticality and risk assessments of processes, equipment, and instruments and ensures that operating and calibration ranges and tolerances are appropriate for processes being validated.
- Partners with development and quality organizations to evaluate products and processes, including prior development, analytical, and manufacturing data, to ensure critical/key process parameters, operating targets and ranges, and controls are defined, justified and documented.
- Actively participates during all phases of validation; plans, documents and executes validation activities, and leads validation team, including consultants and contractors if applicable, and supervises executions.
- Participates in the generation and/or update of validation master plans and reports status to management.
- Participates as applicable in product and process trend reviews and annual product reviews to ensure processes remain in controlled validated state.
- Manages master validation system which tracks all required qualifications and validations, including periodic revalidations or validation associated with changes in equipment, processes, materials, or controls.
- Ensures all qualification and validation activities comply with applicable Change Control procedures and product applications. Responsible for Validation department evaluation and approval of equipment and process change controls to ensure compliance to company standards, procedures, and applicable regulatory requirements.
- Oversees or performs investigations of failures, non-conformances, or deviations from protocol, standard operating procedure, or process requirements, and assesses impact upon qualification or validation status. Ensures all issues, deviations and non-conformances are resolved prior to report approval.
- Ensures test methods supporting qualification or validations are scientifically sound, formally documented, and validated or compendial, as applicable.
- Work with Quality Unit to ensure that product is not released to commercial distribution until all validation requirements have been met and reports approved.
- Initiate and enforce necessary improvements and corrections; oversee contractors conducting validation.
- Establish priorities and schedule activities to ensure timelines and milestones are met.
Qualifications and Experience:
- BS or MS in Science or Engineering discipline
- Minimum 10 years’ experience in biotech/pharma Validation projects or equivalent combination of education and experience.
- Extensive experience (minimum 5 years) in validation design, performance, data analysis, and document preparation, including sterile aseptic processing, autoclave equipment, and sterile Water For Injection (WFI) systems.
- High level of integrity and desire to comply with regulations and corporate standards.
- Knowledge of EU/international and US cGMP regulations for pharmaceutical guidelines, manufacturing operations, metrology requirements, validation procedures and practices.
- Excellent verbal and written communication, interpersonal and communication skills.
- Exhibits sound judgment by evaluating problems thoroughly, soliciting input and ideas, and reaching appropriate conclusions, assessments, and corrective actions where applicable.
- Appropriately challenges the status quo and uses knowledge and experience to continuously improve work processes.
- Experience supervising others and managing a department.
- Experience in a pharmaceutical or FDA regulated company required.
Desirable Skills:
- Experience in pharma and/or biotech cGMP aseptic manufacturing equipment and procedures.
- Good working knowledge of use of statistics in calibrations and validation.
- Experience in failure mode analysis, statistical and risk assessment tools.
Physical Working Conditions:
This is a full– time position for work in a laboratory environment. The position requires wearing personal protective equipment. Occasionally, may require lifting or moving equipment up to 20 pounds and may require standing for extended durations throughout the day. Upon request, reasonable accommodations will be offered to enable individuals with disabilities to perform essential functions. There is little to no travel required of this position, with the exception of required training and possible conference or event attendance.
About Armata Pharmaceuticals, Inc.:
Armata is a clinical-stage biotechnology company focused on the development of precisely targeted bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of the United States and Canada, Armata is developing proprietary synthetic phage candidates to target an undisclosed infectious disease agent. Armata is committed to advancing phage with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.
Pay: $120,000 - $150,000 per year
Send cover letter and CV to: careers@armatapharma.com
Research Associate – Pharmacology
About this Position:
The Research Associate position will support the research and development effort by performing in vitro microbiological testing/analysis.
Job description and technical requirements:
- Carry out microbiological, molecular and biochemical assays (bacterial kill curves, antibiotic MICs, biofilm eradication, cytotoxicity, PBMC stimulation)
- Execute analytical assays using recombinant proteins and/or antibodies (SDS-PAGE, Western Blot, ELISA, MSD)
- Work with and maintain infectious bacteria with aseptic technique
- Develop and optimize new assays as needed
- Conduct semi-high throughput screening
- Process, analyze and organize large data sets
- Perform cross-functional tasks to support product development
- Assist in general upkeep of laboratory and maintain a clean and organized work environment
- Maintain laboratory notebook and accurate records of daily experiments
- Understand and comply with company standard operating procedures and safety procedures
- Read and understand scientific language, literature and publications as necessary
- Other duties as assigned
Qualifications and Experience:
- Must have a Bachelor’s or Master’s Degree in Microbiology, Cell Biology, Chemistry, Chemical Engineering, Physical Chemistry or related field with experience in microbiology
- Must have prior laboratory experience in a lab or research setting
- Hands on experience and knowledge of different types of purification systems (including: tangential flow filtration, AKTA chromatography systems)
- Experience working with and maintaining bacteria with excellent aseptic technique
- Experience performing microbiological plating techniques a plus
- Understanding of statistics and statistical software to interpret experimental results
- Ability to quickly learn new techniques, instruments, software, and assays
- Excellent English communication and reading/writing skills
- Must be reliable, organized, detail oriented, and a self-starter with the ability to prioritize and work with minimal supervision
- Strong team-player and able to work well in small groups and independently
- Familiarity with protein/virus purification techniques is a plus (Size Exclusion, Ion-Exchange, etc.)
- Strong additional interest and experience in chemistry, engineering, and/or physics is a plus
- Familiarity with GMP and working with SOPs is a plus
Physical Working Conditions:
This is a full– time position for work in a laboratory environment. The position requires wearing personal protective equipment. Occasionally, may require lifting or moving equipment up to 20 pounds and may require standing for extended durations throughout the day. Upon request, reasonable accommodations will be offered to enable individuals with disabilities to perform essential functions. There is little to no travel required of this position, with the exception of required training and possible conference or event attendance.
About Armata Pharmaceuticals, Inc.:
Armata is a clinical-stage biotechnology company focused on the development of precisely targeted bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of the United States and Canada, Armata is developing proprietary synthetic phage candidates to target an undisclosed infectious disease agent. Armata is committed to advancing phage with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.
Pay: $30.00 - $35.00 per hour
Send cover letter and CV to: careers@armatapharma.com
Associate Scientist/Scientist – Process Development
About this position:
The Scientist will work in the Process Development group to design, develop, and optimize methods for upstream and downstream processing of bacteriophage at large scale. This role is also expected to work closely with Manufacturing group in the transfer of downstream methods to support regulatory approval processes.
Job description and technical requirements:
- Research, develop, optimize, and implement robust and scalable strategies for improving upstream and downstream manufacturing processes of phage, with an emphasis on downstream processes
- Monitor existing processes and products for quality and efficiency
- Scale up the production process, make changes to components or materials, and process parameters to ensure quality is maintained during large-scale production
- Execute and support process development activities and projects using technical experience, engineering principles, and equipment knowledge
- Conduct experiments and analyses as part of a variety of research and development activities such as small-scale studies, scale-up studies, technology transfer and process development following Design of Experiments
- Investigate and advise on alternative materials and equipment to improve efficiency and quality
- Oversees day-to-day operations of the Process Development purification labs. Maintains constant supply of materials, maintenance services etc. for the efficient function of labs
- Actively participate as a member of multi-functional project teams, executing projects from concept to practical application
- Evaluate and summarize the experimental results, develop, and test hypotheses to improve understanding of downstream purification strategies, yield, purity, and recovery
- Prepare internally reviewed technical reports, CMC documents, and oral presentations
Qualifications and Experience:
- MS or PhD degree in Engineering, Biochemistry, Biotechnology, or closely related discipline with minimum of 3 years industry experience in protein purification development
- Working knowledge of scale up and scale down principles for fermentation, chromatography and filtration unit operations and column packing procedures
- Hands on experience and knowledge of different types of chromatography resins and capsule formats
- Hands on experience with purifying proteins using equipment such as chromatography purification systems (e.g., ÄKTA, AZURA, BioRad, Sartorius), TFF and NFF systems (e.g., ÄKTA crossflow, Sartorius TFF). Experience with filtration and chromatography.
- Working knowledge of protein chemistry, protein analytics and bioprocess technology
- Experience with downstream process development specific to phage or large molecular complexes is a plus
- Experience in process equipment selection and procurement
- Fundamental understanding and/or exposure to cGMP environment is desirable
- Experience and/or exposure to preparation of CMC sections of regulatory submissions is desirable
- Strong oral and written communication skills. Must be able to communicate effectively with all echelons of Management and staff
- Sound understanding of statistical experimental design and analysis, such as design of experiments, is a plus
- Ability to quickly integrate into a fast-paced team, learning new techniques and protocols as needed
- Excellent English communication and reading/writing skills
- Must be reliable, organized, detail oriented, and a self-starter with the ability to prioritize and work with minimal supervision
- Strong team-player and able to work well in small groups and independently
- Self-motivated, organized, capable of working independently, as well as in a collaborative/group environment to collaborate with manufacturing staff on experimental studies and GMP manufacturing
Physical Working Conditions:
This is a full– time position for work in a laboratory environment. The position requires wearing personal protective equipment. Occasionally, may require lifting or moving equipment up to 20 pounds and may require standing for extended durations throughout the day. Upon request, reasonable accommodations will be offered to enable individuals with disabilities to perform essential functions. There is little to no travel required of this position, with the exception of required training and possible conference or event attendance.
About Armata Pharmaceuticals, Inc.:
Armata is a clinical-stage biotechnology company focused on the development of precisely targeted bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat bacterial infections using its proprietary bacteriophage-based technology. Armata is developing and advancing a broad pipeline of natural and synthetic phage candidates, including clinical candidates for Pseudomonas aeruginosa, Staphylococcus aureus, and other pathogens. In addition, in collaboration with Merck, known as MSD outside of the United States and Canada, Armata is developing proprietary synthetic phage candidates to target an undisclosed infectious disease agent. Armata is committed to advancing phage with drug development expertise that spans bench to clinic including in-house phage specific GMP manufacturing.
Pay: $90,000 - $115,000 per year
Send cover letter and CV to: careers@armatapharma.com
