scientist in lab

Pipeline Overview

Armata’s goal is to demonstrate the safety, tolerability and definitive efficacy of multiple therapeutic phage candidates in randomized controlled clinical trials required for regulatory approval and to support commercialization in both acute and chronic indications of high unmet medical need. Armata’s phage cocktails target key antibiotic-resistant and difficult-to-treat pathogens on the World Health Organization’s global priority pathogens list, inclduing Pseudomonas aeruginosa and Staphylococcus aureus. Armata’s fully integrated product development capabilities enable the discovery of optimal phage product candidates, and include the effective adaptation of phages to engineered host cells, essential for efficient process development and resulting in improved purity, stability, and manufacturability, to power rigorous clinical trials. Microbiological surveillance and synthetic biology capabilities drive long-term product life cycle management.

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ProgramProductDiscoveryPreclinicalIND-ClearedPhase 2Partner
Pseudomonas aeruginosa
Respiratory Infections
AP-PA02

CF

Swarm logo
 
AP-PA02

NCFB

tailwind logo
 
Unpartnered
AP-PA03

Pneumonia

 
Unpartnered
Staphylococcus aureus
AP-SA02

Bacteremia

disarm logo
 
US DoD*
AP-SA02

PJI

inFlexion logo
 
Unpartnered
Pseudomonas aeruginosa
Respiratory Infections
DiscoveryPreclinicalIND-ClearedPhase 2
Target: AP-PA02Partner:

CF

Swarm logo
 
Target: AP-PA02Partner: Unpartnered

NCFB

tailwind logo
 
Target: AP-PA03Partner: Unpartnered

Pneumonia

 
Staphylococcus aureus
DiscoveryPreclinicalIND-ClearedPhase 2
Target: AP-SA02Partner: US DoD*

Bacteremia

disarm logo
 
Target: AP-SA02Partner: Unpartnered

PJI

inFlexion logo
 

CF: cystic fibrosis; NCFB: non-CF bronchiectasis; PJI: prosthetic joint infection
SWARM-P.a. NCT Number; NCT04596319; Cystic Fibrosis Foundation TrialFinder
diSArm NCT Number: NCT05184764
Tailwind NCT Number: NCT05616221
*Department of Defense (Naval Medical Research Command, US Army Medical Research Acquisition Activity, Defense Health Agency)